Variable generalization performance of a deep learning model to detect pneumonia in chest radiographs: A cross-sectional study - PLOS MEDICINE

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Zech, J. R. et al. Variable generalization performance of a deep learning model to detect pneumonia in chest radiographs: A cross-sectional study. PLoS Med. 15, e1002683 (2018).

https://doi.org/10.1371/journal.pmed.1002683

Investigation into the generalization performance of weakly supervised CNN classifiers for pneumonia between hospital systems. Due to the difference in the underlying generating functions for the data at each site, despite obtaining good held-out test performance on-site, models had notable performance drops when tested at other sites.

Eric Oermann